Las Vegas murals. The self-guided walking tour of more than a dozen murals includes the hand-painted images of heroes of medicine located on the side of the El Centro Family Care building (emblazoned with a ribbon that reads “Healthcare is a human right!”) and murals of water spirits, sacred birds, and vintage cars. Free.

The Anderson Museum of Contemporary Art in Roswell, featuring a vast collection from over 300 artists-in-residence, provides a self-guided tour enhanced by expert staff. Photograph courtesy of the Anderson Museum of Contemporary Art.

Anderson Museum of Contemporary Art. The Roswell museum doesn’t offer traditional tours, but the staff is always on hand to answer questions. The wide-ranging collection contains works from more than 300 artists who have completed the artist-in-residence program. “No matter how you wander through the museum, every room is captivating,” says Miranda Howe, museum staffer and former artist-in-residence. “You’ll be surprised by the quality and quantity of our collection.” Free.

Discover the stunning variety of turquoise, from sky blue to sea green and bright white, at Albuquerque's Turquoise Museum. Photograph of the Turquoise Museum.

Turquoise Museum. Located in downtown Albuquerque, the museum houses stones that are among the most breathtaking in the world, particularly if you happen to like sky blue, sea green, or bright white. “Most people don’t know that the majority of turquoise is actually white,” says executive director Jacob Lowry. $20 self-guided tour (includes admission fee), $90 private tour.

Through the Mesa Prieta Petroglyph Project, small groups can explore the Wells Petroglyph Preserve in Velarde. Photograph courtesy of Mesa Prieta Petroglyph Project.

Mesa Prieta Petroglyph Project. Visitors wishing to see this stunning collection of stone art must reserve tickets online and wait for the map to be revealed. Intimate groups of approximately six are taken on a several-hour walking excursion through the Wells Petroglyph Preserve, in Velarde, to learn about this unique art form and the people who practiced it. $220 (free for tribal members).

Read more: Atop a millennia-old, windswept mesa, Acoma Pueblo guides continue to tell the long story of a stunning place—on their own terms.